Research & Development

Syngenta has a deep understanding of plants, based on many decades of research and development. Around 4,000 employees at five main R&D centers and numerous field stations around the world are dedicated to raising crop yields and improving quality.

In 2008, the Company invested $969 million in R&D, again placing us among the industry leaders. With projects spanning crop protection, seeds and biotechnology, Syngenta has a uniquely diverse platform. This enables us to co-operate across traditional business lines and provide ideal combinations of genetic and chemical solutions to meet the challenge of raising growers' productivity.

One of the best examples of successful crossbusiness collaboration is Seed Care. We create maximum value for growers by combining selected seed traits with chemical treatments that protect the seed from the day it is sown.

Our Crop Protection and Seeds pipelines (see pages 25 and 29) provide clear evidence of the common direction and interlinkage of our research. Both pipelines are targeting drought tolerance technologies ranging from chemical treatment to drought tolerant corn seeds which can improve yield in conditions of limited water availability. We also see potential synergies between our second generation trait technology and our crop protection portfolio..

Innovation, life cycle management

International co-operation between R&D teams accelerates the pace of innovation, bringing new products to market more quickly and increasing the return on investment. Recent changes in our processes include simultaneous management of previously sequential development phases. This has enabled us to reduce the average time from a compound's discovery to its market introduction by about two years. Syngenta now has an overall R&D process that is among the fastest in the crop protection industry. In Seeds, we have brought traits such as AGRISURE® RW to market with record speed.

The R&D process for chemicals is still a lengthy one - around eight years - with environmental testing a key element throughout. Respect for the environment is inherent in the development of our products, and is a cornerstone of our commitment to make agriculture more sustainable.

Life cycle management is also an integral part of our R&D investment. It enables us to maximize the value of our compounds and to meet the challenge of dealing with living organisms - weeds, diseases and insects - that can frequently develop resistance to existing solutions. The significantly increased sales potential for our fungicide AMISTAR®, for example, reflects our ability to combine it with other products to achieve new effects and solutions. Life cycles in Seeds are continuously extended through the use of molecular-assisted breeding to bring new varieties to market.

New facilities, additional partners

Following on from the opening of our chemical R&D center in Goa, India, in 2007, Syngenta took significant steps to strengthen further its global R&D capacity. In April, we officially opened the Chemistry Research laboratories and Seed Care Institute at our existing site in Stein, Switzerland. At the same time we announced the opening of a new biotechnology center in Beijing, China. This facility will concentrate on early-stage evaluation of GM traits for key crops such as corn and soybean, in the areas of yield improvement, drought resistance, disease control and biomass conversion for biofuels.

We are also investing £35 million at our R&D centre at Jealott's Hill in the UK, which focuses on the development of new herbicides. The investment will enhance the center's industry-leading technological capability and will accelerate further the delivery of new products to market.

Reseach at Jealott's Hill is complemented by the work of Syngenta Biotechnology Inc (SBI), based at Research Triangle Park in North Carolina, USA, which focuses on biotechnology solutions including herbicide tolerant crops.

As well as the extension of our own global R&D organization, we continue to partner with numerous other companies and institutions. Additions to our network of collaborations around the world in 2008 included agreements with Athenix Corporation for the discovery of novel corn insect and soybean cyst nematode resistance genes, and with Dow AgroSciences® to evaluate compounds for our Seed Care portfolio. In total, Syngenta is involved in over 400 scientific collaborations worldwide.

Our venture capital fund LSPB announced two additional minority equity investments last year. One is in Asoyia, a seed company developing soybean with low linolenic acid oil; the other is in IBI, which develops and manufactures portable testing systems for micro-organisms, proteins and small molecules. These investments increase the fund's portfolio to six companies.

Strong networks, wide recognition

Attracting and retaining talent is key to our success in R&D. A part of this lies in enabling and motivating employees by giving them access to Syngenta's global network and full awareness of its potential. In 2008, we continued our series of "Syngenta Science Live" information exchange events which provided a broad forum for engagement at sites around the world. We also began the follow-up series "Science Matters" which will leverage this engagement at a more technical and scientific level.

Our Syngenta Fellows organization for distinguished company scientists held two internal colloquia, and again awarded prizes to younger colleagues for their first-class R&D work.

Syngenta last year won external accolades for innovative R&D work that helps to address serious global challenges. The most prominent of these was a World Business and Development Award for the development and successful introduction of tropical sugar beet.

Innovation

Innovation

Speedy new soybean transformation

Transformation – the insertion of new genes – plays a central role in delivering new traits in plants. In 2006, patent restrictions for established soybean transformation technology challenged Syngenta to develop an entirely new approach. In response, a small group of scientists at Syngenta Biotechnology Inc. (SBI) in the USA developed the new approach in less than one year, managing highly complex intellectual property issues while creating a reliable and efficient soybean transformation technology. Other companies have taken ten times longer to achieve equivalent goals.

© 2009 Syngenta